Infection Due to Clostridium difficile Among Elderly Residents of a Long-Term-Care Facility
作者： A. E. Simor , S. L. Yake , K. Tsimidis
关键词: Diarrhea 、 Odds ratio 、 Medicine 、 Internal medicine 、 Clostridium difficile 、 Epidemiology 、 Intensive care medicine 、 Antibiotics 、 Fecal incontinence 、 Carriage 、 Antibiotic-associated diarrhea
摘要: In a study of the epidemiology infection due to Clostridium difficile at long-term-care facilities, we conducted point-prevalence surveys and obtained stool samples from residents receiving antibiotics those developing diarrhea during 1 year 350-bed nursing home an adjoining 280-bed chronic-care hospital. C. and/or its cytotoxin was detected in 236 specimens 94 residents. Only 16 (17%) these individuals had time detected. The prevalence ranged 2.1% 8.1% 7.1% 14.7% organism recovered six (8.8%) 68 antibiotics, four developed antibiotic-associated diarrhea. receipt antibiotic treatment within previous 8 weeks (odds ratio [OR], 7.9), presence nasogastric or gastrostomy feeding tube (OR, 6.5), urinary fecal incontinence 2.5), more than three underlying diseases 2.0) were statistically significant independent variables associated with infection. Typing isolates by restriction-endonuclease analysis indicated that most infections this facility endogenous enteric carriage organism, little evidence cross-infection.
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