Interactions between Lactobacilli and Antibiotic-Associated Diarrhea

摘要: Publisher Summary Antibiotic-associated diarrhea (AAD) is probably the most common manifestation of normal microflora alteration caused by antimicrobial treatment. AAD may be divided into two types: uncomplicated or nonspecific AAD, and Clostridium difficile-associated diarrheas (CDAD). However, studies particularly CDAD have shown that damaging intestinal lactobacilli play an important role in pathogenesis these diseases, some can successfully used for protection against other AAD. This chapter focuses on concerning impact different external factors, antibiotics, various groups indigenous evaluates experimental animal models CDAD. approach could predict, which microbes are able to restore symbiosis help develop further applications microbial interference therapy prophylaxis difficile infections. The also discusses human clinical trials with non-pathogenic commensal been considered as probiotics beneficial health effects, including prevention amelioration