Effect of Lactobacillus acidophilus on antibiotic-associated gastrointestinal morbidity: a prospective randomized trial.

作者: M C Weissler , W G Yarbrough , S P Dorrestein , A F Drake , C G Garrett

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摘要: Oral antibiotic therapy can alter the gastrointestinal microflora and result in troublesome complaints. Patients who have experience with broad-spectrum antibiotics may be reluctant to start or comply due associated discomfort. In field of otolaryngology, oral is commonplace, patient intolerance a particular compromise less effective choice. Yogurt, which contains Lactobacillus acidophilus, often recommended by practitioners help reduce side effects therapy. We wanted objectively evaluate effect orally administered L. acidophilus on Twenty-seven outpatients, 10 years age older, ear, sinus, throat infections, whom amoxicillin/clavulanate was felt choice, were randomly assigned only, treatment groups. Each advised nursing staff consume well-balanced diet, detailed explanation medication schedule given. A questionnaire given each at conclusion The data analyzed using Spearman's rank-order correlations. Concomitant significant decrease complaints yeast superinfection. Almost all patients (89%) reported resolution infection during course believe that use warranted

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