Mitotic catastrophe and cancer drug resistance: A link that must to be broken
作者： Irina V. Sorokina , Vladimir Gogvadze , Boris Zhivotovsky , Tatiana V. Denisenko
DOI: 10.1016/J.DRUP.2015.11.002
关键词: Mitotic catastrophe 、 Apoptosis 、 Mitosis 、 Cancer research 、 Genome instability 、 Cancer 、 Carcinogenesis 、 Bioinformatics 、 Programmed cell death 、 Cell cycle 、 Biology
摘要: An increased tendency of genomic alterations during the life cycle of cells leads to genomic instability, which is a major driving force for tumorigenesis. A considerable fraction of tumor …
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