Microbial genomes from non-human primate gut metagenomes expand the primate-associated bacterial tree of life with over 1000 novel species

作者: Serena Manara , Francesco Asnicar , Francesco Beghini , Davide Bazzani , Fabio Cumbo

DOI: 10.1186/S13059-019-1923-9

关键词: Human geneticsElusimicrobiaSymbiosisHuman microbiomeGenetic algorithmEvolutionary biologyMetagenomicsBiologyMicrobiomeGenome

摘要: Humans have coevolved with microbial communities to establish a mutually advantageous relationship that is still poorly characterized and can provide a better understanding of the human microbiome. Comparative metagenomic analysis of human and non-human primate (NHP) microbiomes offers a promising approach to study this symbiosis. Very few microbial species have been characterized in NHP microbiomes due to their poor representation in the available cataloged microbial diversity, thus limiting the potential of such comparative …

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