The decay of bacterial messenger RNA.

摘要: Publisher Summary The many demonstrations that the Escherichia coli (E. ) rne gene product (RNase E) is involved in messenger RNA (mRNA) decay have given real impetus to study of this unusual protein's properties and role. recent attention polyadenylylation bacterial mRNAs discovery plays a role turnover an E. plasmid-specific show mRNA has similarities eukaryotic process. Functional refers inactivation messenger's template activity, whereas chemical degradation itself. decay, as process distinct from cleavages initiate degradation, been demonstrated for only few mRNAs. Specific messengers half-lives range about 0.5 20 minutes. rates are actively regulated, thus, affecting yields proteins synthesized. Unique bacteria, portions polycistronic may at different rates, independent size segment or its position transcript. Overall, cells major metabolic function. constitutes half cells' synthesis; actual amount related their growth rate.