Mechanistic Models of Asymmetric Reductions

摘要: Oxidation and reduction are the most fundamental processes in both biological metabolism organic reactions. Organic chemists have developed a variety of reducing agents with hope extending their power improving selectivity to be utilized for modern synthesis. However, much better reductions had been taking place living organisms long time before people chemistry. These reactions fascinating because outstanding features respect reactivity selectivity, which can considered as results catalysis by an oxidoreductase. Namely, general, biochemical proceed rapidly selectively under mild conditions without using high temperature strong acid or base catalyst. In addition, it should noted that enzymatic stereospecific. As knowledge these increases great many investigations biochemistry, encouraged mimic such excellent own systems. attempts aimed not only at developing new type agent properties synthesis, but also obtaining information on mechanism simplified models complex