Analytical rotors and methods for analysis of biological fluids

作者: Boris Braynin , Tammy Leigh Burd , Vladimir Ostoich , Carol T. Schembri

DOI:

关键词: Biological fluidsAnalytical chemistryVolume (thermodynamics)Capillary actionChemistryRotor (electric)PlasmaReagent

摘要: An analytical rotor (10) for separating cellular components from a biological sample includes plurality of internal chambers and passages combining the cell-free with one or more reagents distributing to individual test wells (92). The necessary such as whole blood include measuring chamber (40), an overflow (44), separation (60), reagent (80). (40) (44) have capillary dimensions so that initial volume partitions therebetween, filling first provide preselected volume. (60) is located radially outward both (80) spinning causes measured flow into (60). A collection (90) formed receive plasma Further (92) around periphery (90). Testing separated volumes may be performed without removing rotor.