Perfluoroalkylation reactions of (hetero)arenes

摘要: Perfluoroalkylation reactions of arenes have not been the subject intense study as has case for trifluoromethylation aromatics. However, new synthetic methods proposed achieving homolytic aromatic substitution with perfluoroalkyl moieties begun to claim a relevant role in functionalization reactions, revealed by interesting properties large chains. Methods Ar–Rf bonding can be classified into thermal and photochemical, which turn make use transition metals or non-metal catalyzed. Reactions are mainly radical nature. Radical introducing Rf resulted being most popular versatile options available chemists.