Cholostase und Leberinsuffizienz beim Intensivpatienten

摘要: Cornerstones of the diagnostic investigations disturbances in liver function are analysis and sophisticated evaluation serum enzymes, bilirubin ammonia. Coagulation factors, albumin cholinesterase levels indicators hepatic metabolic capacity. Dynamic assessment complex functions allows quantification activity excretory function. Imaging techniques permit visualization size texture liver, vascular supply perfusion as well an gall bladder extra-hepatic intra-hepatic bile ducts. Manifold causes for cholestasis and/or dysfunction known, such ventilation with high pressure, total parenteral nutrition, shock, hypoxia certain drugs. Obstructive requires reconstitution duct drainage, while non-obstructive primarily treatment causative disease. The symptomatic therapy insufficiency is rarely possible via direct cause, but mostly specific management secondary organ dysfunctions related to including circulatory failure, hepatorenal syndrome encephalopathy. In rare cases a temporary surrogate necessary. molecular absorbent recirculating system (MARS), form extracorporeal dialysis, introduced modality failure.