Antibiotic Therapy for Acute Otitis, Rhinosinusitis, and Pharyngotonsillitis

摘要: Classification of otitis media and bacterial rhinosinusitis into acute, recurrent chronic impacts treatment decisions. Other variables importance include the child’s age, symptom severity, prior history daycare attendance. The etiology both acute (AOM) (ABRS) are similar, with predominant pathogens being Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis. Symptomatic adjunctive therapies other than pain relievers limited value. Guidelines have been promulgated for antibiotic selection AOM ABRS. Amoxicillin is recommended as first line. Amoxicillin/clavulanate, cefuroxime, cefpodoxime, cefdinir preferred oral second-line agents. Duration therapy may be shortened to 5 days many cases. Group A beta hemolytic streptococci (GABHS) major tonsillopharynx requiring treatment. GABHS sensitive in vitro penicillins, macrolides, cephalosporins. To eradicate GABHS, concentrations throat must exceed minimum defined time spans that vary drug. Penicillin choice endorsed by all guidelines. Cephalosporins produce better bacteriologic clinical cure rates penicillin; this superiority outcomes has increasing over two decades.