Role of gamma probe-assisted intraoperative sentinel lymph node evaluation in predicting axillary breast cancer metastasis after neoadjuvant chemotherapy.

摘要: Objective Intraoperative sentinel lymph node biopsy is a universally accepted technique to identify patients who are candidates for axillary dissection during breast cancer surgery. However, there controversy over its use in underwent preoperative neoadjuvant chemotherapy. This study aimed examine the diagnostic value of gamma probe-assisted intraoperative examination with frozen section had undergone Methods retrospective included 94 tumors diagnosed stage IIA, IIB or IIIA invasive locoregional metastasis surgical treatment after Intraoperatively, sampling was done using radioactive colloid and probe materials were examined method. Patients positive nodes resection. Histopathological all samples postoperatively. Results In 87 (92.6%), could be identified The sensitivity, specificity accuracy method predicting macro 85.7, 86.5 86.2%, respectively, 5.7% false negative rate. Conclusions Sentinel identification scintigraphy seems feasible efficient terms differentiating that require surgery, even when they have received Further large prospective studies allowing subgroup analyses warranted.