Causes of evolutionary rate variation among protein sites

作者: Julian Echave , Stephanie J. Spielman , Claus O. Wilke

DOI: 10.1038/NRG.2015.18

关键词: Mutation rateMolecular evolutionMutation (genetic algorithm)Sequence (medicine)Evolutionary biologyComputational biophysicsZoologyA proteinProtein coreBiologyVariation (linguistics)

摘要: … according to RSA and secondary structure (for example, helix, sheet, coil, turn, and so on) … a protein structure would probably be more tolerant to mutations than a site in a less flexible …

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