A codon-based model of nucleotide substitution for protein-coding DNA sequences.
作者： Nick Goldman , Ziheng Yang
DOI: 10.1093/OXFORDJOURNALS.MOLBEV.A040153
关键词: Biology 、 Nonsynonymous substitution 、 Substitution model 、 Synonymous substitution 、 Substitution matrix 、 Ka/Ks ratio 、 Codon usage bias 、 Transversion 、 Computational biology 、 DNA codon table
摘要: … We use a 6 1 X 61 rate matrix Q = (Q,,), where Q& (i # j) … , elements Q,, are fixed so that the row sums of Q equal zero, … that essentially consist of amino acid substitution probabilities, P(t), …
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