The placental specific gene, PLAC1, is induced by the Epstein-Barr virus and is expressed in human tumor cells
作者： Xia Wang , Melody C Baddoo , Qinyan Yin
关键词: Biology 、 Gene 、 Haematopoiesis 、 Gene expression profiling 、 Epstein–Barr virus 、 Cell culture 、 Cancer 、 Lymphoma 、 Virus 、 Virology
摘要: Background The Epstein-Barr virus (EBV) is a causal agent in number of malignancies humans including hematopoietic tumors and non-hematopoietic tumors. Burkitt’s lymphoma cell lines containing the have been shown to form nude mice while clonal derivatives such which viral genome has lost do not (JID 177: 1194-1201, 1998; JV 72: 9150-9156, 68: 6069-6073, 1994). The re-introduction EBV into these negative BLs reconstitutes tumor phenotype. Thus, EBV-induced cellular genes play critical role EBV-related
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