A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction
作者： P. Szankasi , G. Smith
关键词: Exonuclease 1 、 Base pair 、 DNA Exonuclease 、 Schizosaccharomyces pombe 、 DNA 、 DNA repair 、 Mutation 、 Biology 、 Mutant 、 Genetics
摘要: Exonuclease I (Exo I) from Schizosaccharomyces pombe, a 5'-->3' double-stranded DNA exonuclease, is induced during meiotic prophase I. The exo1 gene member of family related repair genes, including RAD2/rad13/xpgc and YKL510/rad2, conserved yeast to humans. An mutant displays mutator phenotype alters activity the ade6-M387 marker effect. These results suggest that Exo acts in pathway corrects mismatched base pairs.
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