Cross-talk between phosphorylation and SUMOylation regulates transforming activities of an adenoviral oncoprotein.
作者： P Wimmer , P Blanchette , S Schreiner , W Ching , P Groitl
DOI: 10.1038/ONC.2012.187
关键词: Signal transducing adaptor protein 、 SUMO protein 、 Biology 、 Suppressor 、 Phosphorylation 、 Cell biology 、 Transcription (biology) 、 Co-Repressor Proteins 、 Molecular biology 、 HEK 293 cells 、 Death-associated protein 6
摘要: … We show here that the adenoviral oncoprotein E1B-55K is a substrate of the SUMO conjugation system, which is directly linked to its C-terminal phosphorylation. This regulative …
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