A Direct Electron Microscopic Immunocytochemical Study of IgM Paraproteinemic Neuropathy

作者: M. Mata , S. N. Kahn , D. J. Fink

DOI: 10.1001/ARCHNEUR.1988.00520300113031

关键词: AntibodyIn vivoPathogenesisCompact myelinElectron microscopicSural nerveImmunohistochemistryImmunoglobulin DepositionPathologyMedicine

摘要: • Direct electron microscopic immunohistochemistry of the sural nerve a patient with neuropathy and an IgM k paraprotein demonstrated that immunoglobulin was deposited throughout compact myelin. These findings support notion deposition plays role in pathogenesis vivo.

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