The monoclonal gammopathies (paraproteins).

摘要: Publisher Summary This chapter discusses the pathogenesis of monoclonal gammopathies, including their cause, animal models, and role T B lymphocytes, cytogenetic aspects, molecular biology. It focusses on recognition proteins in clinical chemistry laboratory, a practical classification gammopathies. The presents long-term follow-up data group patients with gammopathy undetermined significance (MGUS). differentiation benign from malignant gammopathies is examined, association other diseases discussed. antibody activity presented, biclonal idiopathic Bence Jones proteinuria are Genetic factor important There several well-documented reports familial clusters two or more first-degree relatives multiple myeloma. Analysis urine essential for Sulfosalicylic acid Exton's reagent best detection protein. Electrophoresis immunoelectrophoresis were performed all serum Rheumatoid arthritis associated