Effects of Chlorhexidine-Encapsulated Mesoporous Silica Nanoparticles on the Anti-Biofilm and Mechanical Properties of Glass Ionomer Cement.
作者： Huiyi Yan , Hongye Yang , Kang Li , Jian Yu , Cui Huang
DOI: 10.3390/MOLECULES22071225
关键词: Anti biofilm 、 Streptococcus mutans 、 Glass ionomer cement 、 Nuclear chemistry 、 Nanoparticle 、 Restorative material 、 Dentistry 、 Chlorhexidine 、 Materials science 、 Mesoporous silica
摘要: One of the primary causes for failure glass ionomer cement (GIC) is secondary caries. To enhance anti-microbial performance GIC without affecting its mechanical properties, chlorhexidine (CHX) was encapsulated in expanded-pore mesoporous silica nanoparticles (pMSN) to synthesize CHX@pMSN. CHX@pMSN added at three mass fractions (1%, 5%, and 10% (w/w)) powder as experimental groups. Pure set control group. The anti-biofilm properties from each group were tested. results demonstrated that CHX successfully on/into pMSN, encapsulating efficiency 44.62% ability significantly enhanced all groups (p 0.05). In conclusion, adding 1% (w/w) led conspicuous had no adverse effect on this restorative material. This study proposes a new strategy preventing caries by using CHX@pMSN-modified GIC.
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