The clinical correlates of neurological soft signs in chronic schizophrenia.

摘要: Among 16 chronic schizophrenic in-patients, all had at least one neurological soft sign (NSS), and 6 (40%) definite neurodysfunction. NSS TD scores were highly intercorrelated, significantly correlated with neuroleptic drug exposure. positively both positive negative symptoms cognitive impairment but not cerebral ventricular size on CT. Patients neurodysfunction more psychopathology, than those without. Cerebral sizes family histories of schizophrenia similar in groups. The presence may be a simple important way identifying subgroup schizophrenics neurodevelopmental predisposing abnormalities, vulnerability to TD.