Nanotechnology applications in thoracic surgery

作者: Sophie C. Hofferberth , Mark W. Grinstaff , Yolonda L. Colson

DOI: 10.1093/EJCTS/EZW002

关键词: Tumor resectionMedicinePathologyDrug deliveryTreatment of lung cancerLymph node mappingDocetaxelCardiothoracic surgeryIntensive care medicineLung cancerApplications of nanotechnology

摘要: Abstract Nanotechnology is an emerging, rapidly evolving field with the potential to significantly impact care across full spectrum of cancer therapy. Of note, several recent nanotechnological advances show particular promise improve outcomes for thoracic surgical patients. A variety nanotechnologies are described that offer possible solutions existing challenges encountered in detection, diagnosis and treatment lung cancer. Nanotechnology-based imaging platforms have ability patients malignancies through technological intraoperative tumour localization, lymph node mapping accuracy resection. Moreover, nanotechnology poised revolutionize adjuvant Common chemotherapeutic drugs, such as paclitaxel, docetaxel doxorubicin, being formulated using various drug delivery, whereas nanoparticle (NP)-based technologies can monitor microenvironment facilitate molecularly targeted Although early nanotechnology-based delivery systems promise, next frontier therapy development 'theranostic' multifunctional NPs capable integrating diagnosis, monitoring, targeting controlled release into unifying platforms. This article provides overview key emerging may find clinical application surgery near future.

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