Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes

作者: Rasmus Ribel-Madsen , Mario F. Fraga , Stine Jacobsen , Jette Bork-Jensen , Ester Lara

DOI: 10.1371/JOURNAL.PONE.0051302

关键词: MethylationPromoterDNA methylationMonozygotic twinBisulfite sequencingBiologyGeneGeneticsCpG siteAdipose tissueGeneral Biochemistry, Genetics and Molecular BiologyGeneral Agricultural and Biological SciencesGeneral Medicine

摘要: Background Monozygotic twins discordant for type 2 diabetes constitute an ideal model to study environmental contributions to type 2 diabetic traits. We aimed to examine whether …

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