Laboratory preparedness and response with a focus on arboviruses in Europe

作者: C.B. Reusken , M. Ieven , L. Sigfrid , I. Eckerle , M. Koopmans

DOI: 10.1016/J.CMI.2017.12.010

关键词: Context (language use)Clinical manifestationPolitical sciencePreparednessCorporate governancePublic healthArbovirus InfectionsScientific literatureGlobal healthPublic relations

摘要: Abstract Background The global health burden of arboviruses is continuously rising, which results in increasing pressure on local and (inter)national laboratory infrastructures. Timely accurate diagnosis cases one the main pillars for public clinical responses to an arbovirus emergence. Aims sources This narrative review aims summarize recent advances identify needs preparedness response activities, with a focus viruses transmitted by arthropods Europe. based evidence extracted from PubMed searches, Public Health experiences authors authors' opinions substantiated peer-reviewed scientific literature. Content We illustrate importance inter-epidemic activities ensure adequate responses. describe status endemicity emergence Europe thereby highlighting need these viruses. discuss components pitfalls broader context current landscape international research, networks. complexity described. Implications Outbreak plans look beyond national reference laboratories, include first-line responding onsite hospital laboratories strengthening such capacity capability as required depending nature outbreak. In particular, infections complicated existence geographic overlap circulation numerous arboviruses, manifestation between many other aetiologies cross-reactivity related serology testing. Inter-epidemic strong networks addressing issues. However, mushrooming European requires governance bring next level.

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