Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery.

作者: Luisa Pascucci , Valentina Coccè , Arianna Bonomi , Diletta Ami , Piero Ceccarelli

DOI: 10.1016/J.JCONREL.2014.07.042

关键词: Cell cultureTumor microenvironmentChemistryImmunologyPaclitaxelCell biologySecretionMicrovesiclesMesenchymal stem cellIn vitroDrug delivery

摘要: Mesenchymal stromal cells (MSCs) have been proposed for delivering anticancer agents because of their ability to home in on tumor microenvironment. We found that MSCs can …

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