作者: L Gianni , C M Kearns , A Giani , G Capri , L Viganó
DOI: 10.1200/JCO.1995.13.1.180
关键词: Metabolism 、 Paclitaxel 、 Pharmacology 、 Pharmacodynamics 、 Cancer 、 Chemotherapy 、 Medicine 、 Toxicity 、 Pharmacokinetics 、 Disposition
摘要: PURPOSE To characterize and model the disposition of paclitaxel in humans and define a pharmacodynamic relationships between paclitaxel disposition and its toxicity and efficacy. …