Pediatric desmoid tumor: retrospective analysis of 63 cases.

作者: L B Faulkner , S I Hajdu , U Kher , M La Quaglia , P R Exelby

DOI: 10.1200/JCO.1995.13.11.2813

关键词: Negative marginRadiation therapyPositive MarginsResectionHead and neckAge at diagnosisRetrospective analysisTrunkSurgeryMedicine

摘要: PURPOSEThis study was conducted to evaluate clinical prognostic factors predictive of the probability recurrence desmoid tumor (DT).PATIENTS AND METHODSSixty-three patients with histologically confirmed diagnosis DT were retrospectively studied. Median age at 13 years. Patient distribution by site as follows: 61% extremities, 18% head and neck, 13% trunk (including 5% intraabdominal), 8% multicentric lesions. All had partial or complete resections; 20 also received radiotherapy and/or chemotherapy.RESULTSAt a median follow-up time 6 years since first treatment, overall actuarial having one more recurrences 75%. Age, sex, site, size, number previous no significant impact on likelihood recurrence. The only factor associated an increased proportion recurrence-free negative margin resection (70% v 15% positive margins; P = .006). Of four than 3 ...

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