Plant Anticancer Agents XXXIX: Triterpenes from Iris Missouriensis (Iridaceae)
作者： Sui-Ming Wong , Yoshiteru Oshima , John M. Pezzuto , Harry H.S. Fong , Norman R. Farnsworth
关键词: Spectral analysis 、 Triterpene 、 Iris (anatomy) 、 Chemical correlation 、 Iridaceae 、 Chemistry 、 Stereochemistry 、 Terpene 、 Spectral properties 、 Iridoid 、 Pharmaceutical Science
摘要: Employing the roots of Iris missouriensis, two known triterpenes, iso-iridogermanal and zeorin, were isolated identified. As presently reported, they found to demonstrate cytotoxic activity toward cultured P-388 cells (ED50 = 0.1 1.1 μg/mL, respectively). Additionally, a new triterpene that demonstrated an ED50 8.5 μg/mL was isolated. On basis spectral analysis chemical correlation with structure shown be 6α-hydroxy-A'-neogermmacer-22(29)-en-30-oic acid (missourin).
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