Biocidic medical devices, implants and wound dressings
作者： Gleb Zilberstein , Shmuel Bukshpan
DOI:
关键词: Materials science 、 Medical device 、 Biomedical engineering
摘要: The present invention discloses a medical device selected from group consisting of devices, implants wound dressings, comprises at least one insoluble proton sink or source (PSS). is provided useful for killing living target cells (LTCs), otherwise disrupting vital intracellular processes and/or intercellular interactions the LTC upon contact. PSS comprises, inter alia, (i) providing buffering capacity; and (ii) means conductivity electrical potential. effectively pH homeostasis balance within confined volume LTCs while efficiently preserving LTCs' environment.
lens.org 参考文章(70)
Ira Skolnik, Mark Hirsh, Jane Hirsh, Mark Trumbore, Sprayable formulations for the treatment of acute inflammatory skin conditions ,(2005)
Tina L. Palmieri, David G. Greenhalgh, Topical treatment of pediatric patients with burns: a practical guide. American Journal of Clinical Dermatology. ,vol. 3, pp. 529- 534 ,(2002) , 10.2165/00128071-200203080-00003
Issam Raad, Robert Tcholakian, A multipurpose anti-microbial silastic sheath system for the prevention of device-related infections ,(1996)
W J Marshall, P S Choban, Leukopenia secondary to silver sulfadiazine: frequency, characteristics and clinical consequences American Surgeon. ,vol. 53, pp. 515- 517 ,(1987)
Kent Crossley, Method and apparatus to prevent infections ,(2001)
Tung-Liang Lin, Min-Shyan Sheu, Ionic antimicrobial coating ,(2002)
Richard J Zdrahala, David J Lentz, Birendra K Patnaik, Expanded PTFE implantable prosthesis with improved blood and tissue compatibility and superior patency ,(1995)
Hans-Dietrich Polaschegg, Peritoneal dialysis solution with taurolidine ,(2003)
James W. Reding, Talmadge Kelly Keene, James A. Patterson, John A. Thompson, Hemostatic agent, method and carrier for applying a blood clotting agent ,(2001)
Vladimir Ritter, Marina Ritter, Compositions of microspheres for wound healing ,(1998)