作者: Tina L. Palmieri , David G. Greenhalgh
DOI: 10.2165/00128071-200203080-00003
关键词: Dermatology 、 Debridement 、 Resuscitation 、 Pharmacotherapy 、 Wound healing 、 Surgery 、 Dermis 、 Silver sulfadiazine 、 Medicine 、 Mafenide 、 Burn injury
摘要: Over 440 000 children receive medical attention for burn injuries each year in the US. Burn wound infections are a major source of morbidity and mortality these patients. Infected wounds not only heal more slowly, but also may lead to systemic infections. The factors that contribute complications both size depth wound. is usually categorized into first-degree (superficial, involving epidermis), second-degree (partial thickness, epidermis dermis), third-degree (full through epidermis, dermis, fat). Burns will within 2 weeks at least should generally be referred surgeon possible excision grafting, due increased risk infection scarring. dynamic. Proper treatment minimizes extent injury, whereas improper (lack proper wound-care, edema formation, lack resuscitation) actually increase and/or Topical antimicrobial agents have been shown decrease wound-related when used appropriately. goal topical therapy control microbial colonization, thus preventing development invasive A wide variety available wounds, including ointments, creams, biological nonbiological dressings. antimicrobials choice include bacitracin, neomycin, silver sulfadiazine mafenide.