Method for the in vitro detection and differentiation of pathophysiological conditions

作者: Stefan Russwurm

DOI:

关键词: PathophysiologyMolecular biologyBiomarker (cell)Nucleic acidGeneIn vitroBiologyPolynucleotideReference geneBiochemistry

摘要: The invention relates to a method for the in vitro detection and/or differentiation progress observation of pathophysiological conditions with aid sample nucleic acids, including determination gene activities by means plurality polynucleotides, at least one internal reference gene, and formation an index value from single determined normalized multigene biomarker indicating condition.

参考文章(10)
Hans-Peter Deigner, Stefan Russwurm, Method for the prediction of individual disease course in sepsis ,(2005)
Hans-Peter Saluz, Peter F. Zipfel, Eberhard Straube, Hans-Peter Deigner, Stefan Russwurm, Konrad Reinhart, Method for recognising acute generalised inflammatory conditions (sirs), sepsis, sepsis-like conditions and systemic infections ,(2004)
Dan L. Longo, Andrew P. Feinberg, Minoru Ko, Christine A. Iacobuzio-Donahue, Methods of screening for cell proliferation or neoplastic disorders ,(2005)
James A. Garrett, Keith Thornton, Richard Lee Moore, Sha-Shaw Wang, William A. Keating, Craig C. Whiteford, William A. Nussbaumer, Diagnosis of sepsis ,(2006)
Hans-Peter Deigner, Hans Peter Saluz, Stefan Russwurm, Reference genes for the normalization of gene expression analysis data ,(2008)