Autonomic Nerves Versus Prostaglandins in the Control of Rat and Rabbit Testicular Capsular Contractions in vivo and in vitro1
作者： James L. Hargrove , Legrande C. Ellis
DOI: 10.1095/BIOLREPROD14.5.651
关键词: Autonomic agent 、 Biology 、 Contractility 、 Endocrinology 、 Internal medicine 、 Muscle contraction 、 Stimulation 、 Prostaglandin 、 In vivo 、 Acetylcholine 、 Reserpine 、 Cell biology 、 General Medicine
摘要: The tonus and rate of spontaneous contractions measured in vivo from the tunicaalbugineaof rabbit testes were augmented by epinephrine, acetylcholine prostaglandin (PG)F2 �. Neither reserpine, dibenamine nor atropine decreased autorhythmic contractility. Indomethacin injections ip significantly mean amplitude testicular contractions. This treatment effaced motility two eleven preparations. Injections 5,8,11,14-eicosatetraynoic acid (TYA) did not decreasetheamplitudeof contraction. Electrical stimulation spermatic artery (site thespermaticnerve) rabbits rats failed to alter or motility. above evidence suggests that local factors such as PG5 may contribute more smooth muscle activity tunica albuginea rabbittestesthan do autonomic nerves. rhythmical observed vivo, however,continuedinthe presenceof indomethacin bathing medium, requirestimulationby fortheirorigination. Rat testes, unlikerabbit contract rhythmically vivo. Isolated rat testescontractedin responseto administered PGF20, while PGE1 abolished induced Such modulators muscular feasibly could intratesticular pressure for intact animal.
oup.com
osti.gov
biolreprod.org参考文章(14)
L. C. Ellis, J. M. Johnson, J. L. Hargrove, Cellular Aspects of Prostaglandin Synthesis and Testicular Function Prostaglandins in Cellular Biology. pp. 385- 398 ,(1972) , 10.1007/978-1-4684-2844-5_20
Thomas S. Leeson, Frank B. Cookson, The mammalian testicular capsule and its muscle elements Journal of Morphology. ,vol. 144, pp. 237- 253 ,(1974) , 10.1002/JMOR.1051440208
B. A. CROSS, T. D. GLOVER, The hypothalamus and seminal emission. Journal of Endocrinology. ,vol. 16, pp. 385- 395 ,(1958) , 10.1677/JOE.0.0160385
C. BELL, J. R. McLEAN, The autonomic innervation of the rat testicular capsule. Reproduction. ,vol. 32, pp. 253- 258 ,(1973) , 10.1530/JRF.0.0320253
A. -F. Holstein, Ch. Weiss, Über die Wirkung der glatten Muskulatur in der Tunica Albuginea im Hoden des Kaninchens; Messungen des interstitiellen Druckes Zeitschrift für Die Gesamte Experimentelle Medizin einschließlich experimentelle Chirurgie. ,vol. 142, pp. 334- 337 ,(1967) , 10.1007/BF02044812
Rod R. Seeley, James L. Hargrove, Raymond T. Sanders, Legrande C. Ellis, Rabbit testicular capsular contractions--prostaglandins, cyclic adenosine 3',5'-monophosphate and epinephrine. Biochemical Pharmacology. ,vol. 23, pp. 2969- 2976 ,(1974) , 10.1016/0006-2952(74)90271-8
AKIRA RIKIMARU, TAKEO MARUYAMA, MASAFUMI SHIRAI, ISAO DENDO, Pressure Recording of Contraction of the Dog Testis The Tohoku Journal of Experimental Medicine. ,vol. 108, pp. 305- 306 ,(1972) , 10.1620/TJEM.108.305
AKIRA RIKIMARU, MASAFUMI SHIRAI, Responses of the Human Testicular Capsule to Electrical Stimulation and to Autonomic Drugs The Tohoku Journal of Experimental Medicine. ,vol. 108, pp. 303- 304 ,(1972) , 10.1620/TJEM.108.303
MASAFUMI SHIRAI, KEIICHI SASAKI, AKIRA RIKIMARU, A histochemical investigation of the distribution of adrenergic and cholinergic nerves in the human male genital organs. Tohoku Journal of Experimental Medicine. ,vol. 111, pp. 281- 291 ,(1973) , 10.1620/TJEM.111.281
TORBJÖRN MALMFORS, CHARLOTTE SACHS, Direct studies on the disappearance of the transmitter and changes in the uptake-storage mechanisms of degenerating adrenergic nerves. Acta Physiologica Scandinavica. ,vol. 64, pp. 211- 223 ,(1965) , 10.1111/J.1748-1716.1965.TB04171.X