Progesterone receptors as a prognostic factor in Stage II breast cancer.

作者: Gary M. Clark , William L. McGuire , Charles A. Hubay , Olof H. Pearson , J. S. Marshall

DOI: 10.1056/NEJM198312013092240

关键词: RegimenPrognostic factorReceptorStage ii breast cancerAdjuvantAdjuvant therapyInternal medicineEndocrine systemEstrogen receptorMedicineEndocrinology

摘要: Abstract The presence of estrogen receptors in breast cancers is now accepted as a predictor extended disease-free survival, but the relative value progesterone for this purpose has not been established. We have examined both along with other risk factors 189 patients receiving adjuvant therapy Stage II cancer. either or was positively correlated survival when analyzed separately, whether regimen included an endocrine component. However, and were together multivariate models, more significant than that predicting time to recurrence, regardless what variables model. These data suggest determination progesterone-receptor concentration equal greater estrogen-receptor ...

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