Heterogeneity of genetic alterations in primary human breast tumors
作者： Iqbal Unnisa Ali , Rosette Lidereau , Robert Callahan
DOI: 10.1007/978-1-4613-1733-3_2
关键词: Disease 、 Gene duplication 、 Hormone receptor 、 Etiology 、 Bioinformatics 、 Breast cancer 、 Mouse mammary tumor virus 、 Mutation 、 Biology 、 Cancer
摘要: The etiology of human breast cancer is thought to involve a complex interplay among genetic, hormonal, and dietary factors that are superimposed on the physiological status host [1, 2]. As consequence, several different types tumors can be distinguished by histopathological criteria, chromosomal abnormalities, hormone receptor status, other biochemical characteristics. However, attempts derive cohesive picture how various participate in have been confounded lack information specific genetic mutations associated with initiation or progression disease. Three general approaches used attempt identify cancer.
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