作者: Jan G. M. Klijn , John A. Foekens
DOI: 10.1007/978-3-642-75948-2_4
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摘要: New directions in research regarding adjuvant treatment of patients with early breast cancer concerns (potential) new modalities and better selection high- low-risk patients. In the current discussion on application systemic therapy primary cancer, identification is a major issue [1]. Several classical (Table 1) second generation prognostic factors (proliferation rate, DNA ploidy, oncogenes, growth factor receptors, some glycoproteins) are used for making therapeutic decisions [2]. At present, more than 60 parameters have been reported can be classified into 4 main groups: patient characteristics, blood parameters, tumour characteristics response to 2).