Prolonged Shedding of Human Coronavirus in Hematopoietic Cell Transplant Recipients: Risk Factors and Viral Genome Evolution.

作者: Chikara Ogimi , Alexander L Greninger , Alpana A Waghmare , Jane M Kuypers , Ryan C Shean

DOI: 10.1093/INFDIS/JIX264

关键词: Logistic regressionPolymerase chain reactionVirologyViral loadHematopoietic cellPneumoniaCoronavirusGenome evolutionHuman coronavirusImmunologyMedicine

摘要: … mNGS among 5 subjects showed single-nucleotide polymorphisms from OC43 and NL63 … of HCoV and initial high viral load in transplant recipients. In addition, prior high-dose steroid …

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