Fabrication of Polymer-Protein Hybrids.
作者： Yuanyuan Ju , Yue Zhang , Hanying Zhao
关键词: Polymer 、 Coupling reaction 、 Nanoparticle 、 Nanotechnology 、 Chemistry 、 Polymerization 、 Chemical reaction 、 Covalent bond 、 Molecular recognition 、 Self-healing hydrogels
摘要: Rapid developments in organic chemistry and polymer promote the synthesis of polymer-protein hybrids with different structures biofunctionalities. In this feature article, recent progress achieved conjugates, protein-nanoparticle core-shell structures, nanogels/hydrogels is briefly reviewed. The conjugates can be synthesized by "grafting-to" or "grafting-from" approach. coupling reactions polymerization methods used bioconjugates are Protein molecules immobilized on surfaces nanoparticles covalent noncovalent linkages. specific interactions chemical employed discussed. Finally, a general introduction to environmentally responsive cross-linking molecular recognition provided.
omicsonline.org 参考文章(215)
Linda Hasadsri, Jörg Kreuter, Hiroaki Hattori, Tadao Iwasaki, Julia M. George, Functional Protein Delivery into Neurons Using Polymeric Nanoparticles Journal of Biological Chemistry. ,vol. 284, pp. 6972- 6981 ,(2009) , 10.1074/JBC.M805956200
Zeng-Ying Qiao, Rui Zhang, Fu-Sheng Du, De-Hai Liang, Zi-Chen Li, Multi-responsive nanogels containing motifs of ortho ester, oligo(ethylene glycol) and disulfide linkage as carriers of hydrophobic anti-cancer drugs. Journal of Controlled Release. ,vol. 152, pp. 57- 66 ,(2011) , 10.1016/J.JCONREL.2011.02.029
Johannes Pall Magnusson, Sara Bersani, Stefano Salmaso, Cameron Alexander, Paolo Caliceti, In Situ Growth of Side-Chain PEG Polymers from Functionalized Human Growth Hormone-A New Technique for Preparation of Enhanced Protein-Polymer Conjugates Bioconjugate Chemistry. ,vol. 21, pp. 671- 678 ,(2010) , 10.1021/BC900468V
Robert Pelton, Temperature-sensitive aqueous microgels. Advances in Colloid and Interface Science. ,vol. 85, pp. 1- 33 ,(2000) , 10.1016/S0001-8686(99)00023-8
Paolo Zucca, Enrico Sanjust, Inorganic Materials as Supports for Covalent Enzyme Immobilization: Methods and Mechanisms Molecules. ,vol. 19, pp. 14139- 14194 ,(2014) , 10.3390/MOLECULES190914139
Debora Bontempo, Karina L. Heredia, Benjamin A. Fish, Heather D. Maynard, Cysteine-reactive polymers synthesized by atom transfer radical polymerization for conjugation to proteins. Journal of the American Chemical Society. ,vol. 126, pp. 15372- 15373 ,(2004) , 10.1021/JA045063M
Omprakash Yemul, Toyoko Imae, Covalent-bonded immobilization of lipase on poly(phenylene sulfide) dendrimers and their hydrolysis ability. Biomacromolecules. ,vol. 6, pp. 2809- 2814 ,(2005) , 10.1021/BM050285D
Adriano A Mendes, Pedro C Oliveira, Heizir F de Castro, None, Properties and biotechnological applications of porcine pancreatic lipase Journal of Molecular Catalysis B-enzymatic. ,vol. 78, pp. 119- 134 ,(2012) , 10.1016/J.MOLCATB.2012.03.004
Cyrille Boyer, Jingquan Liu, Lingjiun Wong, Michael Tippett, Volga Bulmus, Thomas P. Davis, Stability and utility of pyridyl disulfide functionality in RAFT and conventional radical polymerizations Journal of Polymer Science Part A. ,vol. 46, pp. 7207- 7224 ,(2008) , 10.1002/POLA.23028
Marjoke F. Debets, Sander S. van Berkel, Sanne Schoffelen, Floris P. J. T. Rutjes, Jan C. M. van Hest, Floris L. van Delft, Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition Chem. Commun.. ,vol. 46, pp. 97- 99 ,(2010) , 10.1039/B917797C