2-Cyano indan-1,3-diones

摘要: Pharmaceutical compositions are produced comprising as the active ingredient a compound of formula ##STR1## or pharmaceutically acceptable, nontoxic salt thereof hydrate thereof, wherein R 1 , 2 3 and 4 each hydrogen, halogen, lower alkyl alkoxy, any two groups taken together with carbon atoms to which they joined complete substituted unsubstituted carbocyclic ring, X is bond an oxygen atom, combined inert diluent carrier. Those compounds not all simultaneously hydrogen novel. When bond, may be prepared by reacting appropriately 3-dyanomethylene phthalide base and, thereafter, if desired, converting salt. suitably benzene derivative activated carbonyl group having carbanion NC--CH--R, carboxylic acid ester group, into