Changes in the prevalence of the measles, rubella, varicella-zoster, and mumps virus antibody titers in Japanese pregnant women.

作者: Masachi Hanaoka , Michi Hisano , Noriyoshi Watanabe , Kana Sugawara , Yukari Kambe

DOI: 10.1016/J.VACCINE.2013.03.012

关键词: ImmunityImmunologyRubellaAntibody titerTiterVirologyPregnancyHemagglutination assayVaccinationMedicineMeasles

摘要: Abstract In the present study, immunity against infectious diseases, which are capable of influencing both mother and fetus during pregnancy infant in postnatal period, were assessed pregnant women to elucidate necessity vaccination childbearing age. It was determined that there a trend increases proportion patients had low antibody titers observed at young Overall, after adjusting for age, measles (≤4 via neutralization test [NT]), rubella (≤16 hemagglutination inhibition [HI]), varicella mumps (plus minus or negative on enzyme-linked immunosorbent assay [EIA]) indicated rates measles, rubella, varicella, 27.6%, 16.1%, 3.9%, 23.8%, respectively. Japan, acquired dependent vaccination, whereas natural infection. We recommend be vaccinated delivery, as these vaccines live, thereby, contraindicated pregnancy.

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