Esthesioneuroblastoma: the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and chemotherapy.
作者： Anthony Nichols , Annie Chan , William Curry , Fred Barker , Daniel Deschler
关键词: Medicine 、 General hospital 、 Stage (cooking) 、 Craniofacial 、 Chemotherapy 、 Esthesioneuroblastoma 、 Proton beam radiation 、 Craniofacial resection 、 Proton radiation 、 Surgery
摘要: Objectives: To determine the efficacy of craniofacial resection and proton radiation for management esthesioneuroblastoma (ENB). Design: A retrospective chart review was performed all patients presenting with ENB completely managed at Massachusetts General Hospital (MGH) Eye Ear Infirmary (MEEI) from 1997 to 2006. Setting: tertiary referral center. Main Outcome Measures: Disease-free overall survival. Participants: All MGH MEEI Results: Ten were identified a median follow-up time 52.8 months. Average age presentation 45 years. Nasal obstruction most common symptom. Three presented Kadish stage B disease seven C. No patient had evidence cervical or metastatic presentation. Seven treated resections (CFR) followed by beam without chemotherapy. initial chemotherapy no response. They subsequently underwent CFR radiation. The 5-year disease-free survival rates 90% 85.7%, respectively, Kaplan-Meier analysis. suffered any severe toxicity. Conclusion: can be safely effectively irradiation. Proton irradiation may associated less toxicity than photon role remains unclear.
thieme-connect.de参考文章(30)
James H. Simon, Weining Zhen, Timothy M. McCulloch, Henry T. Hoffman, Arnold C. Paulino, Nina A. Mayr, John M. Buatti, Esthesioneuroblastoma: The University of Iowa Experience 1978–1998 Laryngoscope. ,vol. 111, pp. 488- 493 ,(2001) , 10.1097/00005537-200103000-00020
Sung-Kyun Hwang, Sun-Ha Paek, Dong Gyu Kim, Yoon-Kyung Jeon, Je G. Chi, Hee-Won Jung, Olfactory neuroblastomas: survival rate and prognostic factor. Journal of Neuro-oncology. ,vol. 59, pp. 217- 226 ,(2002) , 10.1023/A:1019937503469
Emmanuel Gay, Laligam N. Sekhar, Elaine Rubinstein, Donald C. Wright, Chandranath Sen, Ivo P. Janecka, Carl H. Snyderman, Chordomas and chondrosarcomas of the cranial base: results and follow-up of 60 patients. Neurosurgery. ,vol. 36, pp. 887- 897 ,(1995) , 10.1227/00006123-199505000-00001
E. L. Kaplan, Paul Meier, Nonparametric Estimation from Incomplete Observations Springer Series in Statistics. ,vol. 53, pp. 319- 337 ,(1992) , 10.1007/978-1-4612-4380-9_25
N. Bhattacharyya, A. F. Thornton, M. P. Joseph, M. L. Goodman, P. C. Amrein, Successful Treatment of Esthesioneuroblastoma and Neuroendocrine Carcinoma With Combined Chemotherapy and Proton Radiation: Results in 9 Cases Archives of Otolaryngology-head & Neck Surgery. ,vol. 123, pp. 34- 40 ,(1997) , 10.1001/ARCHOTOL.1997.01900010038005
Vicente A. Resto, David W. Eisele, Arlene Forastiere, Marianna Zahurak, Ding-Jen Lee, William H. Westra, Esthesioneuroblastoma: the Johns Hopkins experience. Head and Neck-journal for The Sciences and Specialties of The Head and Neck. ,vol. 22, pp. 550- 558 ,(2000) , 10.1002/1097-0347(200009)22:6<550::AID-HED2>3.0.CO;2-0
Sidney Kadish, Max Goodman, C. C. Wang, Olfactory neuroblastoma—A clinical analysis of 17 cases Cancer. ,vol. 37, pp. 1571- 1576 ,(1976) , 10.1002/1097-0142(197603)37:3<1571::AID-CNCR2820370347>3.0.CO;2-L
Jannis Constantinidis, Helmut Steinhart, Michael Koch, Michael Buchfelder, Anne Schaenzer, Manfred Weidenbecher, Heinrich Iro, Olfactory Neuroblastoma: The University of Erlangen-Nuremberg Experience 1975–2000: Otolaryngology-Head and Neck Surgery. ,vol. 130, pp. 567- 574 ,(2004) , 10.1016/J.OTOHNS.2003.10.010
Athanassios Argiris, Jose Dutra, Paraskevi Tseke, Kenneth Haines, Esthesioneuroblastoma : the Northwestern University experience Laryngoscope. ,vol. 113, pp. 155- 160 ,(2003) , 10.1097/00005537-200301000-00029
Philip M. Wade, Roy E. Smith, Michael E. Johns, Response of esthesioneuroblastoma to chemotherapy report of five cases and review of the literature Cancer. ,vol. 53, pp. 1036- 1041 ,(1984) , 10.1002/1097-0142(19840301)53:5<1036::AID-CNCR2820530504>3.0.CO;2-3