Does being easily moved to tears as a response to psychological stress reflect response to treatment and the general prognosis in patients with rheumatoid arthritis
作者： Nagashima M , Nakajima A , Yoshino S , Ishii H , Tanno M
DOI:
关键词: Endocrinology 、 Medicine 、 Tears 、 Immunopathology 、 Gastroenterology 、 Hydrocortisone 、 Autoimmune disease 、 Internal medicine 、 Glucocorticoid 、 Rheumatoid arthritis 、 Blood plasma 、 Interleukin 6
摘要: Objective Psychological stress affects the condition of patients with rheumatoid arthritis (RA). We evaluated neuroendocrine and immune responses (NEIRs) in peripheral blood to psychological induced by deep emotion tears RA. Methods compared levels plasma cortisol interleukin-6 (IL-6), CD4/CD8 ratio, natural killer (NK) cell activity between easily controlled RA (CRP < 1.0 mg/dl) those difficult-to-control ≥ before after session. Results had a greater influence on NEIRs than mg/dl). The cortisol, IL-6, ratio were lower, while NK was higher who not moved tears. Patients apt obtain good control within one year. Conclusion better are as an emotional expression; shedding is considered suppress NEIRs, thus preventing buildup stress. more emotionally affected but
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