Laser Doppler study of porcine cauda equina blood flow. The effect of electrical stimulation of the rootlets during single and double site, low pressure compression of the cauda equina.

作者: Andrew R. Baker , Tanya A. Collins , Richard W. Porter , Cecil Kidd

DOI: 10.1097/00007632-199503150-00005

关键词: Spinal cord compressionAnatomyCauda equinaBlood flowLaser Doppler velocimetryAnesthesiaMedicineHemodynamicsSpinal cordSpinal stenosisNeurogenic claudication

摘要: Study Design. This study involved a model of spinal claudication to assess the effect single and double site compressions on blood flow in porcine cauda equina. Real-time monitoring was achieved by using laser Doppler probes. Objectives. To ascertain difference betwee nerve conduction Also, provide possible explanations for mechanisms underlying pathophysiology neurogenic claudication. Summary Background Data. The used based that K. Olmarker. Double as compared with compression equina showed impaired impulse propagation decreased flow. Method. Pigs weighing 22-27 kg were anesthetized exposed dorsal laminectomy sacral first three coccygeal vertebrae. Polyethylene balloons placed over rootlets at third segments, stimulating electrodes positioned proximally evoke motor activity. Electromyographic activity monitored from tail musculature. Laser probes both between distal two sites. Results. Single site, low level did not affect whereas it profoundly. Proximal stimulation caused marked increase flow, which sustained during prolonged compression. diminished concomitantly this Conclusions. Low pressure, significantly reduces prevents required maintain normal neurologic rootlet function. Local failure may therefore be responsible symptoms

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