Modeling of bone failure by cohesive zone models

摘要: Cohesive zone models are a powerful tool for investigations of non-linear deformation and failure processes. For the nanoscale, use cohesive is particularly attractive as ratio interface to volume high, because locally acting bonds between material components can become relevant. The present paper demonstrates relevance modelling approaches development nano-mechanical composite model mineralized collagen fibril, fundamental building block bone. As difficulties exist in determining independent biomechanical effects cross-linking using vitro vivo experiments, computational modeling provide insight into nanoscale Stress-strain curves fibrils were obtained under tensile loading various conditions. Our predicts that elastic mode, yield response final fibril may depend significantly on state cross-linking.