Open Sesame! CXCR4 Blockade Recruits Neutrophils Into the Plaque

作者: Julie Sainz , Masataka Sata

DOI: 10.1161/CIRCRESAHA.107.170241

关键词: Proinflammatory cytokineMyocardial infarctionUnstable anginaAbsolute neutrophil countCXCR4MedicineChemokineInflammationPathologyPathogenesisImmunology

摘要: … CXCR4-expressing neutrophils in the bone marrow. In the circulation, CXCR4 expression increases in aged neutrophils, … /CXCR4 signaling by AMD3465, a specific CXCR4 antagonist, …

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