Potential cellular receptors involved in hepatitis C virus entry into cells.
作者： Daniel Favre , Beat Muellhaupt
关键词: Microvesicles 、 Receptor 、 Virus 、 Antigen 、 CD81 、 Hepacivirus 、 NS2-3 protease 、 Hepatitis C virus 、 Virology 、 Biology
摘要: Hepatitis C virus (HCV) infects hepatocytes and leads to permanent, severe liver damage. Since the genomic sequence of HCV was determined, progress has been made towards understanding functions HCV-encoded proteins identifying cellular receptor(s) responsible for adsorption penetration particle into target cells. Several receptors have proposed, all which are associated with lipid lipoprotein metabolism. This article reviews suggests a general model entry cells, in lipoproteins play crucial role.
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