作者: McKenney Jm
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摘要: The treatment of hypercholesterolemia in the United States begins with recognition elevated low-density lipoprotein cholesterol (LDL-C) as primary target. An optimal LDL-C level has been defined < 100 mg/dL. first step lowering continues to be lifestyle modification, which includes a restriction saturated fat and cholesterol, increased physical activity, weight loss, if applicable. Approximately half all patients levels will ultimately need lipid-lowering drug achieve goals. preferred for first-line most is statin; bile acid resin or niacin can used who cannot tolerate statins are not candidates stain therapy. Combination therapy an option, several combinations showing efficacy (statin plus resin, resin) both triglycerides fibrate, statin niacin, niacin). Successful lipid management treating reach goal level, non-high-density applicable, managing other risk factors coronary heart disease.