作者: Michael J. Strong , Sharon Abrahams , Laura H. Goldstein , Susan Woolley , Paula Mclaughlin
DOI: 10.1080/21678421.2016.1267768
关键词: International research 、 Frontotemporal dementia 、 Psychology 、 Neuroimaging 、 Cognition 、 Psychiatry 、 Spectrum disorder 、 Amyotrophic lateral sclerosis 、 Social cognition 、 Neuropsychology
摘要: AbstractThis article presents the revised consensus criteria for diagnosis of frontotemporal dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research workshop dementia (FTD) and ALS held London, Canada June 2015. Since publication Strong criteria, there have been considerable advances understanding neuropsychological profile patients with ALS. Not only is breadth depth findings broader than previously recognised –– including deficits social cognition language – but mixed may also occur. Evidence now shows that are extremely heterogeneous, affecting over 50% persons When present, these significantly adversely impact patient survival. It recognition this clinical heterogeneity association neuroimaging, genetic neuropathological has led to current re-conceptualisation neu...