作者: Martin R Turner , Kevin Talbot
DOI: 10.1136/PRACTNEUROL-2016-001554
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摘要: An elderly female developed anarthria with prominent emotionality over an 18-month period before specialist neurological assessment. Although tongue electromyography was normal, her corticobulbar signs were consistent amyotrophic lateral sclerosis (ALS), a pattern that, in the absence of functional impairment outside speech and swallowing, is appropriately termed progressive bulbar palsy. Such patients, often females, may remain ambulant independent for many months, sometimes years, despite typically rapid anarthria.1 Electromyography be insensitive to denervation, even when genioglossus sampled, this can contribute diagnostic …