Formation of apatite nano-needles on novel gel derived SiO2-P2O5-CaO-SrO-Ag2O bioactive glasses
作者： Fariborz Sharifianjazi , Nader Parvin , Mohammadreza Tahriri
DOI: 10.1016/J.CERAMINT.2017.08.056
关键词: Bioactive glass 、 Bromide 、 Viability assay 、 Nano- 、 Bone tissue 、 Apatite 、 Nuclear chemistry 、 Fourier transform infrared spectroscopy 、 Scanning electron microscope 、 Mineralogy 、 Materials science
摘要: Abstract A novel SiO 2 -P O 5 -CaO-SrO-Ag bioactive glass containing from 0 to 10 mol% Ag was produced via the sol-gel method. The influence of silver content on in vitro hydroxyapatite (HA) formation, antibacterial and cell viability properties were investigated. apatite shape structure evaluated by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) X-ray diffraction analysis (XRD). results demonstrated that rate formation crystalline HA 5% (BG-5A) higher comparison with other specimens. Formation nano-needles -CaO-SrO-5%Ag surface vitro, after 3 days soaking SBF solution, high bioactivity. alkaline phosphatase (ALP) 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay evaluation methods illustrated presence low (3% O) had stimulating effect promoting both differentiation proliferation G292 osteoblastic cells. Finally, offer specimen BG-5A is well candidate for bone tissue application considerable potential, bioactivity optimal viability.
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