A case of intrahepatic cholangiocarcinoma that was difficult to diagnose prior to surgery: A case report
作者： Ken Nagata , Takahiro Einama , Akifumi Kimura , Michinori Murayama , Hiroteru Takeo
DOI: 10.3892/OL.2018.9666
关键词: Liver tumor 、 Lymphadenectomy 、 Medicine 、 Magnetic resonance imaging 、 Pathology 、 Adenocarcinoma 、 Intrahepatic Cholangiocarcinoma 、 Positron emission tomography 、 Hepatectomy 、 Standardized uptake value
摘要: The present study reports a case of mass-forming intrahepatic cholangiocarcinoma (ICC), which mimicked cholangiocellular carcinoma (CoCC) during imaging and needle biopsy examination. A 51-year-old female with no relevant medical history was referred to the National Defense Medical College hospital an tumor. Computed tomography demonstrated non-homogeneous enhancement in early arterial phase persistent portal equilibrium phases, together notable swelling para-aortic lymph nodes. Gadolinium-ethoxybenzyl diethylenetriamine-pentaacetic acid-enhanced magnetic resonance revealed low signal intensity hepatobiliary phase. liver tumor nodes exhibited increased radiotracer uptake (maximum standardized value=14.0) positron emission tomography. histological examination percutaneous specimen indicated diagnosis CoCC. patient underwent left hepatectomy lymphadenectomy. surgical contained poorly differentiated adenocarcinoma anaplastic changes, immunohistochemically positive for epithelial membrane antigen (at luminal membrane), cytokeratins 7 19, negative α-fetoprotein, hepatocyte-specific antigen, cluster differentiation 56 KIT. Based on these histopathological immunohistochemical findings, diagnosed ICC.
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